一般描述
Lysine analog that inhibits carboxypeptidase B. Promotes rapid dissociation of plasmin by inhibiting activation of plasminogen by streptokinase.
Lysine analog. Inhibits carboxypeptidase B. Promotes rapid dissociation of plasmin by inhibiting activation of plasminogen.
生化/生理作用
Carboxypeptidase B
制备说明
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
储存分类代码
10-13 - German Storage Class 10 to 13
法规信息
监管及禁止进口产品
J E Humphries et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 13(1), 48-55 (1993-01-01)
Binding of plasmin(ogen) to rat C6 glioma cells is saturable and kringle-domain dependent. This interaction was studied as a model of plasmin(ogen) receptor interactions in nucleated mammalian cells. Apparent 125I-plasmin dissociation from C6 cell binding sites was slow; however, the
L F Lin et al.
Biochemistry, 39(16), 4740-4745 (2000-04-19)
Lysine side chains induce conformational changes in plasminogen (Pg) that regulate the process of fibrinolysis or blood clot dissolution. A lysine side-chain mimic, epsilon amino caproic acid (EACA), enhances the activation of Pg by urinary-type and tissue-type Pg activators but
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