生物来源
mouse
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
1A6, monoclonal
种属反应性（根据同源性预测）
all
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... NOS1(4842)
一般描述
Anti-Nitrotyrosine antibody (05-233) cross-linked to protein G agarose by dimethylpimelimidate
免疫原
Nitrated KLH
应用
Anti-Nitrotyrosine Antibody, clone 1A6, agarose conjugate is an antibody against Nitrotyrosine for use in IP.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Oxidative Stress
Oxidative Stress
Suitable for immunoprecipitation and affinity purification.
生化/生理作用
Recognizes nitrated protein.
特点和优势
Format: Gel Immobilized
外形
Protein A purified
Mouse immunoglobulin covalently coupled to protein A agarose beads and provided as a 50% slurry suspended in PBS, pH 7.4, containing 0.05% sodium azide as a preservative.
制备说明
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Nitrated BSA
Nitrated BSA
routinely evaluated by immunoprecipitating nitrated proteins from Nitrotyrosine Immunoblotting Controls (12-354) as detected by subsequent immunoblot analysis using anti-Nitrotyrosine (06-284)
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Myeloperoxidase produces nitrating oxidants in vivo
Gaut, J. P., et al
The Journal of Clinical Investigation, 109, 1311-1319 (2002)
Esteban A Moya et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 66(10), 753-765 (2018-05-19)
Chronic intermittent hypoxia (CIH), main feature of obstructive sleep apnea, produces nitro-oxidative stress, which contributes to potentiate carotid body (CB) chemosensory discharges and sympathetic-adrenal-axis activity, leading to hypertension. The MnSOD enzymatic activity, a key enzyme on oxidative stress control, is
Arun Venkatesan et al.
Molecular brain, 4, 28-28 (2011-06-29)
Methamphetamine (METH) abuse has reached epidemic proportions, and it has become increasingly recognized that abusers suffer from a wide range of neurocognitive deficits. Much previous work has focused on the deleterious effects of METH on mature neurons, but little is
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