16-244
Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2, Alexa Fluor™ 488
clone 9H2, Upstate®, from mouse
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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR™ 488
Clone:
9H2, monoclonal
Application:
FACS, ICC
Citations:
8
biological source
mouse
conjugate
ALEXA FLUOR™ 488
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
9H2, monoclonal
species reactivity
mouse, human
packaging
antibody small pack of 25 μg
manufacturer/tradename
Upstate®
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pTyr1173)
Quality Level
Gene Information
human ... EGFR(1956)
mouse ... Egfr(13649)
General description
175kDa
Immunogen
KLH-conjugated, synthetic peptide containing the Y1173 motif (...NAE[pY1173]LRV...) of the human EGFR
Application
Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2, Alexa Fluor 488 detects level of phospho-EGFR (Tyr1173) & has been published & validated for use in FC & IC.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Biochem/physiol Actions
the motif NAE[pY]LRV corresponding to the major autophosphorylation site of the human EGFR
Preparation Note
1 year at 4°C from date of shipment
Analysis Note
Routinely evaluated by positive immunostaining for phospho-EGFR in A431 cells.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
ALEXA FLUOR is a trademark of Life Technologies
Disclaimer
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Epidermal growth factor inhibition in solid tumours.
Ganti, Apar Kishor and Potti, Anil
Expert opinion on biological therapy, 5, 1165-1174 (2005)
Structure and function of the epidermal growth factor (EGF/ErbB) family of receptors.
Leahy, Daniel J
Advances in Protein Chemistry, 68, 1-27 (2004)
Intrinsic and acquired resistance to EGFR inhibitors in human cancer therapy.
Bianco, Roberto, et al.
Endocrine-Related Cancer, 12 Suppl 1, S159-S171 (2005)
Cetuximab.
Goldberg, Richard M
Nature Reviews. Drug Discovery, Suppl, S10-S11 (2005)
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