176904
Anthrax Lethal Factor Protease Substrate III, Fluorogenic
An N-acetylated, C-7-amido-4-methylcoumarin (AMC) derivative of a 14-mer peptide substrate designed from the MEK-2 template that is useful for measuring Anthrax lethal factor (LF) metalloproteolytic activity with a detection limit of ~5-10 pM.
别名:
Anthrax Lethal Factor Protease Substrate III, Fluorogenic, Anthrax LF Protease Substrate III, Fluorogenic, Bacillus anthracis LF Protease Substrate III, Fluorogenic
质量水平
方案
≥97% (HPLC)
表单
lyophilized
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
溶解性
water: 1 mg/mL
5% acetic acid: 5 mg/mL
DMSO: 5 mg/mL
荧光
λex ~360 nm
λem ~460 nm
运输
wet ice
储存温度
−20°C
一般描述
An N-acetylated, C-7-amido-4-methylcoumarin (AMC) derivative of a 14-mer peptide substrate designed from the MEK-2 template that is useful for measuring Anthrax Lethal Factor (LF) metalloproteolytic activity with a detection limit of ~5-10 pM. Reported to be useful for high-throughput screening of LF inhibitors. Excitation max.: ~360 nm; emission max.: ~460 nm.
生化/生理作用
Cell permeable: no
Primary Target
Measuring Anthrax lethal factor (LF) metalloproteolytic activity
Measuring Anthrax lethal factor (LF) metalloproteolytic activity
Product does not compete with ATP.
Reversible: no
包装
Packaged under inert gas
外形
Supplied as a trifluoroacetate salt.
制备说明
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Ac-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-AMC
Tonello, F., et. al. 2002. Nature418, 386.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持