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Merck
CN

178464

Anti-Apolipoprotein A-II Goat pAb

liquid, Calbiochem®

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关于此项目

UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
—
Citations:
3

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biological source

goat

antibody form

diluted serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

General description

Anti-Apolipoprotein A-II, goat polyclonal, recognizes human apolipoprotein A-II. Does not cross-react with other apolipoproteins. It is validated for immunoelectrophoresis and immunoprecipitation.
Goat polyclonal antibody supplied as diluted serum that has been defibrinated, delipidized and adsorbed by solid phase chromatography. Recognizes the apoplipoprotein-II protein.
Recognizes apolipoprotein A-II. Does not cross-react with other apolipoproteins.
  • Antibody Target Gene Symbol: APOA2
  • Target Synonym: A2, Alp-2, APOAII, APOLIPOPROTEIN A-II, APOLIPOPROTEIN A2, Hdl-1, HDLA2
  • Entrez Gene Name: apolipoprotein A-II
  • Hu Entrez ID: 336
  • Mu Entrez ID: 11807
  • Rat Entrez ID: 25649

    • Immunogen

    Human
    purified human apolipoprotein A-II

    Application

    Immunoelectrophoresis (see comments)

    Immunoprecipitation (see comments)

    Packaging

    Please refer to vial label for lot-specific concentration.

    Physical form

    Serum diluted in 500 mM NaCl, 50 mM Tris-HCl, pH 7.5.

    Preparation Note

    Following initial thaw, aliquot and freeze (-20°C).

    Other Notes

    Monospecific as determined by immunoelectrophoresis (immunoprecipitation) against 2X pooled human serum. Variables associated with assay conditions will dictate the proper working dilution.

    Legal Information

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

    Disclaimer

    Toxicity: Standard Handling (A)

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    存储类别

    10 - Combustible liquids

    wgk

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

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    Kekulawalage Gauthamadasa et al.
    The Journal of biological chemistry, 287(10), 7615-7625 (2012-01-12)
    It is well accepted that HDL has the ability to reduce risks for several chronic diseases. To gain insights into the functional properties of HDL, it is critical to understand the HDL structure in detail. To understand interactions between the
    Cendrine Cabou et al.
    Acta physiologica (Oxford, England), 226(3), e13268-e13268 (2019-03-02)
    The contribution of apolipoprotein A1 (APOA1), the major apolipoprotein of high-density lipoprotein (HDL), to endothelium-dependent vasodilatation is unclear, and there is little information regarding endothelial receptors involved in this effect. Ecto-F1 -ATPase is a receptor for APOA1, and its activity
    Mohammad A Hossain et al.
    BMC biochemistry, 13, 1-1 (2012-01-18)
    ATP-binding cassette transporter A1 (ABCA1) mediates the lipidation of exchangeable apolipoproteins, the rate-limiting step in the formation of high density lipoproteins (HDL). We previously demonstrated that HDL oxidized ex vivo by peroxidase-generated tyrosyl radical (tyrosylated HDL, tyrHDL) increases the availability

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