182730
ASB-C8Ø
A zwitterionic detergent with an aromatic core that is shown to stabilize and solubilize integral membrane proteins by breaking aggregates.
别名:
ASB-C8Ø, C8Ø, 4- n-Octylbenzoylamido-propyl-dimethylammonio Sulfobetaine, C8Ø, 4-n-Octylbenzoylamido-propyl-dimethylammonio Sulfobetaine
质量水平
方案
≥95% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
off-white
溶解性
water: 50 mg/mL
运输
ambient
储存温度
2-8°C
InChI
1S/C23H40N2O4S/c1-4-5-6-7-8-9-12-21-13-15-22(16-14-21)23(26)24-17-10-18-25(2,3)19-11-20-30(27,28)29/h13-16H,4-12,17-20H2,1-3H3,(H-,24,26,27,28,29)
InChI key
AQVJFUZGGMXMED-UHFFFAOYSA-N
一般描述
A zwitterionic detergent (zwittergent®) containing an aromatic core that has been demonstrated to stabilize and solubilize integral membrane proteins by breaking aggregates. Useful for protein analysis and characterization by two-dimensional gel electrophoresis and mass spectrometry techniques. Reported to be superior to CHAPS (Cat. No. 220201) in solubilizing an ion-channel protein and a G-protein coupled receptor (GPCR). In combination with thiourea and urea, also reported to improve the recovery of hydrophobic proteins from Arabidopsis thaliana.
A zwitterionic detergent with an aromatic core that is shown to stabilize and solubilize integral membrane proteins by breaking aggregates. Useful for protein analysis and characterization by two-dimensional (2-D) gel electrophoresis and mass spectrometry techniques. Reported to be superior to CHAPS (Cat. No. 220201) in solubilizing both an anion-channel and a G-protein coupled receptor (GPCR).
包装
Packaged under inert gas
制备说明
Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
其他说明
Henningsen, R., et al. 2002. Proteomics2, 1479.
Molloy, M.P. 2000. Anal. Biochem.280, 1.
Santoni, V., et al. 2000. Electrophoresis21, 3329.
Rabilloud, T., et al. 1999. Electrophoresis20, 3603.
Santoni, V., et al. 1999. Electrophoresis20, 705.
Herbert, B. 1999. Electrophoresis20, 660.
Chevallet, M., et al. 1998. Electrophoresis19, 1901.
Molloy, M.P. 2000. Anal. Biochem.280, 1.
Santoni, V., et al. 2000. Electrophoresis21, 3329.
Rabilloud, T., et al. 1999. Electrophoresis20, 3603.
Santoni, V., et al. 1999. Electrophoresis20, 705.
Herbert, B. 1999. Electrophoresis20, 660.
Chevallet, M., et al. 1998. Electrophoresis19, 1901.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Zwittergent is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Irritant (B)
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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