主要文件

203408-M

BLEOCIN Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem

Name: BLEOCIN Antibiotic, <i>Streptomyces verticillus</i>, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem
Brand: MM

suitable for cell culture

别名:

BLEOCIN Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem

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关于此项目

经验公式（希尔记法）:

C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl

化学文摘社编号:

55658-47-4

分子量:

1613.49

UNSPSC Code:

12352200

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属性

assay

≥85% (HPLC)

Quality Level

100

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

technique(s)

cell culture | mammalian: suitable

color

blue

solubility

water: 10 mg/mL

storage temp.

2-8°C

InChI

1S/C57H89N19O21S2.ClH/c1-22-35(73-48(76-46(22)61)27(14-33(60)80)68-15-26(59)47(62)86)52(90)75-37(43(28-16-65-21-69-28)95-56-45(41(84)39(82)31(17-77)94-56)96-55-42(85)44(97-57(63)92)40(83)32(18-78)93-55)53(91)70-24(3)38(81)23(2)49(87)74-36(25(4)79)51(89)67-13-8-34-71-30(20-98-34)54-72-29(19-99-54)50(88)66-12-7-11-64-10-6-5-9-58;/h16,19-21,23-27,31-32,36-45,55-56,64,68,77-79,81-85H,5-15,17-18,58-59H2,1-4H3,(H2,60,80)(H2,62,86)(H2,63,92)(H,65,69)(H,66,88)(H,67,89)(H,70,91)(H,74,87)(H,75,90)(H2,61,73,76);1H

InChI key

NRVKJXFKQWUKCB-UHFFFAOYSA-N

说明

General description

A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.

A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

Other Notes

Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695.
Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics14, 243.
Ehrenfeld, G.M., et al. 1987. Biochemistry26, 931.
Takita, T., et al. 1972. J. Antibiot. 25, 755.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H315,H317,H319,H334,H335,H361d

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c