208922-M
CaMKII Inhibitor, CK59
The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
CaMKII Inhibitor, CK59, 2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C21H37N7O3
化学文摘社编号:
分子量:
435.56
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
SMILES string
[nH]1nc(c(c1N)N=Nc2ccc(cc2)O)N
InChI
1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)
InChI key
AYZRKFOEZQBUEA-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
semisolid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: 10 mg/mL
Quality Level
General description
A cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50<10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
A cell-permeable Olomoucine analog that acts as a CaMKII inhibitor (IC50<10 M) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 M) and GLUT4 membrane translocation (IC50 = 100 M) in 3T3-L1 adipocytes.
Preparation Note
Following reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Konstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持