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Merck
CN

216201

Sigma-Aldrich

Carboxyatractyloside, Potassium Salt, Xanthium sibiricum - CAS 35988-42-2 - Calbiochem

别名:

Carboxyatractyloside, Potassium Salt, Xanthium sibiricum - CAS 35988-42-2 - Calbiochem, C-ATR, CAT

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关于此项目

经验公式（希尔记法）:
C31H43K3O18S2 · 3H2O
化学文摘社编号:
35988-42-2
分子量:
939.13
UNSPSC代码:
12352200

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方案

≥95% (HPLC)

质量水平

100

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

颜色

white

溶解性

water: 10 mg/mL

运输

ambient

储存温度

−20°C

InChI

1S/C31H46O18S2.2K/c1-14(2)9-21(33)47-24-23(49-51(42,43)44)22(48-50(39,40)41)18(13-32)46-26(24)45-17-11-29(4)19-6-5-16-10-30(19,25(34)15(16)3)8-7-20(29)31(12-17,27(35)36)28(37)38;;/h14,16-20,22-26,32,34H,3,5-13H2,1-2,4H3,(H,35,36)(H,37,38)(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/t16-,17?,18?,19?,20?,22?,23?,24?,25-,26?,29-,30+;;/m1../s1

InChI key

FPJGZZYAZUKPAD-NBKMCPERSA-L

一般描述

This product has been discontinued.



We are offering Carboxyatractyloside potassium salt (Cat. No. C4992) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.






Toxic compound isolated from the plant Xanthium sibiricum. A highly selective and potent inhibitor of adenine nucleotide translocator (ANT) (Ki<10 nM) and inducer of permeability transition pore opening. Stabilizes the nucleoside binding site of ANT on the cytoplasmic side of the inner membrane and blocks the exchange of matrix ATP and cytoplasmic ADP. Does not affect the activity of mitochondrial multiple conductance channel (MCC).

CAS No. refers to that of the free acid.
Toxic compound isolated from the plant Xanthium sibiricum. A highly selective and potent inhibitor of adenine nucleotide translocator (ANT) (Ki<10 nM) and inducer of permeability transition pore opening. Stabilizes the nucleoside binding site of ANT on the cytoplasmic side of the inner membrane and blocks the exchange of matrix ATP and cytoplasmic ADP. Does not affect the activity of mitochondrial multiple conductance channel (MCC). CAS No. refers to that of the free acid.

其他说明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Pebay-Peyroula, E., et al. 2003. Nature426, 39.
Huber, T., et al. 1999. Biochemistry38, 762.
Fiore, C., et al. 1998. Biochimie80, 137.
Lohret, T.A., et al. 1996. J. Biol. Chem.271, 4846.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Toxic (F)

储存分类代码

10-13 - German Storage Class 10 to 13

法规信息

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