234505
Compound 56 - CAS 171745-13-4 - Calbiochem
A cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 6 pM).
别名:
Compound 56 - CAS 171745-13-4 - Calbiochem, 4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline
方案
≥97% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
DMSO: 200 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 6 pM).
A cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 6 pM).
生化/生理作用
Cell permeable: yes
Primary Target
EGFR
EGFR
Product competes with ATP.
Reversible: yes
Target IC50: 6 pM against EGFR
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Bridges, A.J., et al. 1996. J. Med. Chem. 39, 267.
法律信息
Sold under license of U.S. Patent 5,457,105 and European Patent 0,566,266.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Carcinogenic / Teratogenic (D)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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