260684
1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem
A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.
别名:
1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem, DNJ, HCl
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关于此项目
经验公式（希尔记法）:
C6H13NO4 · xHCl
化学文摘社编号:
分子量:
163.17 (free base basis)
MDL编号:
UNSPSC代码:
12352200
质量水平
方案
≥98% (TLC)
表单
crystalline solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
溶解性
water: 100 mM
运输
ambient
储存温度
2-8°C
一般描述
A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.
Specific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis.
生化/生理作用
Cell permeable: no
Primary Target
Glucosidase 1, glucosidase 2
Glucosidase 1, glucosidase 2
Product does not compete with ATP.
Reversible: no
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Suh, K., et al. 1992. J. Biol. Chem. 267, 21671.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta825, 95.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta825, 95.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Irritant (B)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
K Suh et al.
The Journal of biological chemistry, 267(30), 21671-21677 (1992-10-25)
The role of glucosylated oligosaccharides in the biogenesis of the glycoprotein (G protein) of vesicular stomatitis virus was studied in PhaR2.7, a mouse lymphoma cell line deficient in glucosidase II activity. As expected, the great majority of cell-associated G protein
Inhibitors of oligosaccharide processing.
U Fuhrmann et al.
Biochimica et biophysica acta, 825(2), 95-110 (1985-06-24)
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