268320
Daptomycin, Streptomyces sp.
A semi-synthetic cyclic polypeptide antibiotic that is active against vancomycin-resistant gram-positive bacteria, including enterococci and Staphylococcus aureus (MIC50 = 0.13 µg/ml).
别名:
Daptomycin, Streptomyces sp., Cubicin, Dapcin
InChI
1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35?,36-,37?,43+,44+,45+,46+,47+,48+,49+,50-,60+,61?/m1/s1
InChI key
DOAKLVKFURWEDJ-OFNKPWESSA-N
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
off-white to pale yellow
solubility
ethanol: 1 mg/mL (sonication may be required), DMSO: 50 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
General description
Packaging
Other Notes
Cui, L., et al. 2006. Antimicrob. Agents Chemother.50, 1079.
Silverman, J.A., et al. 2003. Antimicrob. Agents Chemother.47, 2538.
Rybak, M.J., et al. 2000. Antimicrob. Agents Chemother.44, 1062.
Legal Information
Disclaimer
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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