EGF, Murine Submaxillary Glands, Receptor Grade

Effective biological range: 5-50 ng/ml.

Native epidermal growth factor from mouse submaxillary glands. Mitogenic for a wide range of ectoderm- and endoderm-derived cells from tissue such as breast, cornea, epidermis, dermis, liver, pancreas, nerve, amnion, and adrenal medulla. Purified by size-exclusion chromatography followed by DEAE ion-exchange chromatography.

Native epidermal growth factor from mouse submaxillary glands. Purified by size-exclusion chromatography. Exhibits mitogenic activity in a wide range of tissues of ectodermal and endodermal origin. Effective at concentrations ranging from 5-50 ng/ml.

determined by mitogenic assay with human foreskin fibroblasts

Reconstitute in culture medium, buffer, H₂O, or 100 mM acetic acid. Wipe the vial with 70% ethanol, add solvent, and swirl gently to dissolve.

Canals, F., et al. 1992. Biochemistry31, 4493.
Cohen, S. 1987. In Vitro Cell. Dev. Biol.23, 239.
Sato, J., et al. 1987. Methods Enzymol.146, 63.
Savage, C.R., and Cohen, S. 1972. J. Biol. Chem.247, 7609.

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Toxicity: Standard Handling (A)