344038
cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem
别名:
cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem, 4-(3,4-Dimethylanilino)-7-(4-(methylsulfonyl)phenyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor III
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: 100 mg/mL
shipped in
ambient
Quality Level
General description
This product has been discontinued.
A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC50 = 0.1 and 10 µM, respectively).
A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC50 = 0.1 and 10 µM, respectively).
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett.17, 6257.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
10-13 - German Storage Class 10 to 13
法规信息
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