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Merck
CN

344038

Sigma-Aldrich

cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem

别名:

cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem, 4-(3,4-Dimethylanilino)-7-(4-(methylsulfonyl)phenyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor III

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关于此项目

经验公式(希尔记法):
C25H23N3O3S
化学文摘社编号:
分子量:
445.53
UNSPSC代码:
12352200
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方案

≥97% (HPLC)

质量水平

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
protect from light

颜色

yellow

溶解性

DMSO: 100 mg/mL

运输

ambient

储存温度

2-8°C

一般描述

This product has been discontinued.



A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC50 = 0.1 and 10 µM, respectively).

A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC50 = 0.1 and 10 µM, respectively).

包装

Packaged under inert gas

制备说明

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett.17, 6257.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Standard Handling (A)

储存分类代码

10-13 - German Storage Class 10 to 13

法规信息

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