Plk2, GST- Fusion, Human, Recombinant, S. frugiperda

Full length, recombinant, human Plk2 fused at the N-terminus to GST and expressed in S. frugiperda insect cells using a baculovirus expression system. Plk2 is a G1 specific kinase that is specifically detected in brain, heart, and lung. Plk2 expression increases in the presence of DNA-damaging agents. The active kinase is useful for the study of Plk2 regulation and inhibitor screening.

Please refer to vial label for lot-specific concentration.

In 100 mM NaCl, 25 mM Tris-HCl, 3 mM DTT, 50% glycerol, 0.05% Tween^®-20 detergent, pH 8.0.

Following initial thaw, aliquot and freeze (-70°C).

Eckerdt, F., et al. 2005. Oncogene24, 267.
Warnke, S., et al. 2004.Curr Biol.14, 1200.

One unit is defined as the amount of enzyme that will phosphorylate 1 pmol SER/THR 16 substrate per min at 30°C, pH 7.5.

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Toxicity: Standard Handling (A)