表单
liquid
一般描述
Recombinant, human granzyme B expressed in E. coli. Granzyme B (GzmB) is a serine protease that is involved in cytotoxic T lymphocyte-induced (CTL) cell death. It is reported to participate in the perforation of target cells and initiation of proteolysis that leads apoptosis. Similar to caspases, granzyme B preferentially cleaves substrate proteins with aspartic acid in the P1 position.
Recombinant, human granzyme B expressed in E. coli. Granzyme B (GzmB) is a serine protease that is used by activated cytotoxic T lymphocytes (CTL) to induce target cell apoptosis. It is involved in the perforation of target cells and initiation of proteolysis that leads the cell into the apoptosis pathway.
应用
Granzyme B, Human, Recombinant, E. coli, is a serine protease used by activated cytotoxic T cells to induce apoptosis. Induces cell perforation and initiates proteolysis leading to cell death.
外形
In TBS, 50% glycerol.
制备说明
Following initial thaw, aliquot and freeze (-70°C).
其他说明
One unit is defined as the amount of enzyme that will hydrolyze 1 nmol Ac-IEPD-pNA per min 25° C, pH 8.0.
警示用语：
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
E Wilharm et al.
The Journal of biological chemistry, 274(38), 27331-27337 (1999-09-10)
Granzymes are granule-stored lymphocyte serine proteases that are implicated in T- and natural killer cell-mediated cytotoxic defense reactions after target cell recognition. A fifth human granzyme (granzyme 3, lymphocyte tryptase-2), renamed as granzyme K (gene name GZMK), has recently been
J L Harris et al.
The Journal of biological chemistry, 273(42), 27364-27373 (1998-10-09)
Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes. Definition of the substrate specificity of granzyme B allows for the identification of in vivo substrates in this process. By using the combinatorial
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