biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(ELISA (1:1000)
Immunoblotting (1:1000))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
Anti-Gsα-Subunit, rabbit polyclonal, specifically recognizes the Gsα-subunit. It is validated for use in ELISA and Western blotting.
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the Gsα-subunit protein.
Recognizes the Gsα-subunit. Does not cross-react with recombinant Giα-1-, Giα-2-, Giα-3-, Goα-, Gqα-, Gtα-1-, or G11α-subunits.
Immunogen
recombinant, rat, brain Gsα-subunit
Application
ELISA (1:1000)Immunoblotting (1:1000)
Other Notes
This antibody reacts specifically with the GTP-binding regulatory protein (G-protein) subunit Gsα. Does not cross-react with recombinant Giα-1-, Giα-2-, Giα-3-, Goα-, Gqα-, Gtα-1-, or G11α-subunits. Variables associated with assay conditions will dictate the proper working dilution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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存储类别
10 - Combustible liquids
wgk
WGK 1
Ruth Goldberg et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 21(5), 703-713 (2006-06-01)
The etiology of skeletal growth retardation accompanying metabolic acidosis is not clear. Using ex vivo models for endochondral ossification, we showed that the cAMP/PKA pathway, probably triggered by proton sensitive G-protein-coupled receptors, is responsible for impaired skeletal growth in acidosis.
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