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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

liquid

不包含

preservative

种属反应性

human, mouse, rat

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(Immunoblotting (1:1000)
Neutralization Studies )

同位素/亚型

IgG

运输

wet ice

储存温度

−70°C

靶向翻译后修饰

unmodified

基因信息

human ... GNAI1(2770)
mouse ... Gnai1(14677)
rat ... Gnai1(25686)

一般描述

Anti-Gqα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa Gqα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies.
Protein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunit proteins.
Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.

免疫原

a synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits

应用

Immunoblotting (1:1000)

Neutralization Studies (see comments)

警告

Toxicity: Standard Handling (A)

其他说明

The antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA86, 7407.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1


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