382155
Histone Deacetylase Substrate, Fluorogenic
别名:
Histone Deacetylase Substrate, Fluorogenic, Boc-Lys(Ac)-AMC, MAL, N-(4-Methyl-7-coumarinyl)-N α-(t-butoxycarbonyl)-N ω-acetyllysinamide
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关于此项目
Assay:
≥98% (HPLC)
Form:
crystalline solid
Quality level:
Storage condition:
OK to freeze, protect from light
assay
≥98% (HPLC)
Quality Level
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
ethanol: 1 mg/mL, DMSO: 5 mg/mL
fluorescence
λex 330 nm, λem 395 nm
shipped in
ambient
storage temp.
−20°C
InChI
1S/C23H31N3O6/c1-14-12-20(28)31-19-13-16(9-10-17(14)19)25-21(29)18(8-6-7-11-24-15(2)27)26-22(30)32-23(3,4)5/h9-10,12-13,18H,6-8,11H2,1-5H3,(H,24,27)(H,25,29)(H,26,30)/t18-/m0/s1
InChI key
SUTRDULVNIPNLW-SFHVURJKSA-N
General description
A fluorogenic substrate for histone deacetylase (HD; excitation maximum: 330 nm; emission maximum: 395 nm).
Note: The histone deacetylase will cleave the Ac group and after the enzymatic reaction 2 peaks will be visible on HPLC. Before the reaction HPLC shows only one peak. The measure of second peak gives the degree of hydrolysis. It is important to use HPLC equipped with a fluorescence detector.
Note: The histone deacetylase will cleave the Ac group and after the enzymatic reaction 2 peaks will be visible on HPLC. Before the reaction HPLC shows only one peak. The measure of second peak gives the degree of hydrolysis. It is important to use HPLC equipped with a fluorescence detector.
Other Notes
Hoffmann, K., et al. 1999. Nucleic Acids Res.27, 2057.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 382155-1MG | 04055977213195 |