382155
Histone Deacetylase Substrate, Fluorogenic
别名:
Histone Deacetylase Substrate, Fluorogenic, Boc-Lys(Ac)-AMC, MAL, N-(4-Methyl-7-coumarinyl)-N α-(t-butoxycarbonyl)-N ω-acetyllysinamide
方案
≥98% (HPLC)
质量水平
表单
crystalline solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
white
溶解性
ethanol: 1 mg/mL
DMSO: 5 mg/mL
荧光
λex 330 nm
λem 395 nm
运输
ambient
储存温度
−20°C
InChI
1S/C23H31N3O6/c1-14-12-20(28)31-19-13-16(9-10-17(14)19)25-21(29)18(8-6-7-11-24-15(2)27)26-22(30)32-23(3,4)5/h9-10,12-13,18H,6-8,11H2,1-5H3,(H,24,27)(H,25,29)(H,26,30)/t18-/m0/s1
InChI key
SUTRDULVNIPNLW-SFHVURJKSA-N
一般描述
A fluorogenic substrate for histone deacetylase (HD; excitation maximum: 330 nm; emission maximum: 395 nm).
Note: The histone deacetylase will cleave the Ac group and after the enzymatic reaction 2 peaks will be visible on HPLC. Before the reaction HPLC shows only one peak. The measure of second peak gives the degree of hydrolysis. It is important to use HPLC equipped with a fluorescence detector.
Note: The histone deacetylase will cleave the Ac group and after the enzymatic reaction 2 peaks will be visible on HPLC. Before the reaction HPLC shows only one peak. The measure of second peak gives the degree of hydrolysis. It is important to use HPLC equipped with a fluorescence detector.
其他说明
Hoffmann, K., et al. 1999. Nucleic Acids Res.27, 2057.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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