385880
Hsp25 Kinase Inhibitor
The Hsp25 Kinase Inhibitor controls the biological activity of Hsp25 KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
Hsp25 Kinase Inhibitor, KKKALNRQLGVAA, MK2 Inhibitor, MAPKAP Kinase-2 Inhibitor, MK2 Inhibitor, KKKALNRQLGVAA, MAPKAP Kinase-2 Inhibitor
质量水平
方案
≥98% (HPLC)
表单
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white
溶解性
DMSO: soluble
water: soluble
运输
ambient
储存温度
−20°C
相关类别
一般描述
A 13-residue, cell-permeable peptide that acts as a potent and selective inhibitor of mammalian heat-shock protein (Hsp25) kinase. Inhibits Hsp25 kinase competitively with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM). [Hsp 25 kinase is also called mitogen-activated protein kinase-activated protein kinase-2 (MK2).]
生化/生理作用
Cell permeable: yes
Primary Target
(Hsp25) kinase
(Hsp25) kinase
Product does not compete with ATP.
Reversible: no
Target Ki: 8.1 µM against (Hsp25) kinase
外形
Supplied as a trifluoroacetate salt.
制备说明
Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.
其他说明
H-Lys-Lys-Lys-Ala-Leu-Asn-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH
Katsoulidis, E., et al. 2005. Cancer Res.65, 9029.
Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.
Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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