表单
liquid
一般描述
Full-length, recombinant, human Hsp90β (amino acids 1-724) fused to a His Tag® sequence at the N-terminus and expressed in S. frugiperda insect cells. Hsp90β a heat shock protein is involved in signal transduction, cell cycle progression, and apoptosis. Moreover, the expression of Hsp90&beta is increased in response to IL-6.
Hsp90β a heat shock protein is involved in signal transduction, cell cycle progression, and apoptosis.
外形
In 400 mM KCl, 40 mM HEPES/KOH, 5% glycerol, pH 7.5.
制备说明
Following initial thaw, aliquot and freeze (-70°C).
法律信息
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10-13 - German Storage Class 10 to 13
法规信息
新产品
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Chrisostomos Prodromou et al.
Current cancer drug targets, 3(5), 301-323 (2003-10-08)
Understanding the mode of action of Hsp90 requires that molecular detail of its interactions with client proteins and co-chaperones are known. The structure determination of the N-terminal domain of Hsp90/Hsp90beta, proof that it is an ATPase, that this activity is
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