407129
D-myo-Inositol 1,4,5-Trisphosphate, 3-Deoxy-3-fluoro-, Hexasodium Salt - CAS 129365-68-0 - Calbiochem
Equipotent to Ins(1,4,5)P3 in releasing intracellular calcium.
别名:
D-myo-Inositol 1,4,5-Trisphosphate, 3-Deoxy-3-fluoro-, Hexasodium Salt - CAS 129365-68-0 - Calbiochem, 3-F-Ins(1,4,5)P3, 6Na
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
Equipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine so it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. May be a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.
Equipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine, hence it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. May be a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Releasing intracellular calcium
Releasing intracellular calcium
Product does not compete with ATP.
Reversible: no
Other Notes
Rubinstein, E., et al. 1992. Blood79, 2901.
Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc.112, 7403.
Bartha, K., et al. 1989. Biochem. J.263, 149.
Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc.112, 7403.
Bartha, K., et al. 1989. Biochem. J.263, 149.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
10-13 - German Storage Class 10 to 13
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