407271
Integrin αMβ₂ Ligand - CAS 307525-40-2 - Calbiochem
别名:
Integrin αMβ₂ Ligand - CAS 307525-40-2 - Calbiochem, 3-(o-Tolyl)-5-(3-phenyl-2-propenylidene)-2-thioxo-1,3-thiazolin-4-one, IMB-10, CD11b Agonist I, CD11b/CD18 Agonist I, CR3 Agonist I, Mac-1 Agonist I, αMβ2 Agonist I
方案
≥98% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
yellow
溶解性
DMSO: 15 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A cell-permeable thioxothiazolidine compound that displays anti-inflammatory properties. Shown to increase cell adhesion and lowers leukemia cell migration in vitro and leukocyte recruitment in vivo and displays anti-inflammatory properties. Binds to and stabilizes integrin αM I domain active conformation and enhances the ligands′ (pro-MMP-9 and fibrinogen) binding ability.
生化/生理作用
Cell permeable: yes
Primary Target
Binds to and stabilizes integrin αM I domain active conformation
Binds to and stabilizes integrin αM I domain active conformation
Product does not compete with ATP.
Reversible: no
包装
Packaged under inert gas
其他说明
Bjorklund, M., et al. 2006. Biochemistry45, 2862.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
10-13 - German Storage Class 10 to 13
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