产品名称
离子霉素钙盐,来源于链霉菌 , Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.
InChI
1S/C41H71O9.Ca/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42;/h11,13,24-33,36-37,39,42,45,48H,12,14-23H2,1-10H3,(H,46,47);/q-1;+2/p-1/b13-11+;/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+;/m1./s1
InChI key
RULWQOBWZOQCOY-SQNLDGQHSA-M
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
white to off-white
solubility
DMSO: 100 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
细胞渗透性:否
主要目的
可用于细胞活化实验
可用于细胞活化实验
产品不与ATP竞争。
可逆:否
Disclaimer
毒性:有害(C)
General description
pH 7-9.5条件下与Ca2+的配合物,具有强烈的紫外吸收。与A23187相比,它没有荧光。有助于研究Ca2+的跨生物膜转运。诱导胚胎皮层神经元凋亡性变性。同时诱导成熟的Burkitt淋巴瘤细胞系发生G1期细胞周期阻滞。通常用于不需要钙剂量反应数据的细胞活化实验。
可用于不需要钙剂量反应数据的细胞活化实验。也可以10 mM的DMSO溶液(货号407953)提供。
Other Notes
Dupuy d′Angeac, A., et al. 1993.J. Cell Physiol.154, 44.
Lee, H.C.1993.J. Biol. Chem.268, 293.
Lee, H.C.1993.J. Biol. Chem.268, 293.
Packaging
用惰性气体包装
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
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