质量水平
方案
≥98% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
off-white
溶解性
ethanol: 10 mg/mL
DMSO: 5 mg/mL
运输
wet ice
储存温度
−20°C
InChI
1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3
InChI key
CLEXYFLHGFJONT-UHFFFAOYSA-N
一般描述
生化/生理作用
Cell permeable: yes
Primary Target
Induces cyclopia by blocking shh (Sonic Hedgehog) signaling
Induces cyclopia by blocking shh (Sonic Hedgehog) signaling
Product does not compete with ATP.
Reversible: no
Target IC50: ~ 500-700 nM blocking shh (Sonic Hedgehog) signaling in s12 cells
包装
Packaged under inert gas
制备说明
Following reconstitution in fresh DMSO, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Slight warming may be required to achieve complete solubilization in ethanol.
其他说明
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Williams, J.A., et al. 2003. Proc. Natl. Acad. Sci. USA100, 4616.
Cooper, M. K., et al. 2003. Nat. Genet.33, 508.
Mistretta, C.M., 2003. Dev. Biol.254, 1.
ten Berge, D., et al. 2001. Development128, 2929.
Cooper, M.K., et al. 1998. Science280, 1603.
Cooper, M. K., et al. 2003. Nat. Genet.33, 508.
Mistretta, C.M., 2003. Dev. Biol.254, 1.
ten Berge, D., et al. 2001. Development128, 2929.
Cooper, M.K., et al. 1998. Science280, 1603.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Toxic (F)
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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