428026
Latrunculin A
from Latrunculia magnifica, ≥85% (HPLC), liquid, actin polymerization inhibitor, Calbiochem
别名:
InSolution Latrunculin A, Latrunculia magnifica
产品名称
Latrunculin A, Latrunculia magnifica, InSolution, ≥85%, 1 mM in DMSO, marine toxin that disrupts microfilament organization in cultured cells
assay
≥85% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
protect from light
shipped in
wet ice
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Inhibitor of microfilament-mediated processes in sperm, eggs, and embryos
Inhibitor of microfilament-mediated processes in sperm, eggs, and embryos
Product does not compete with ATP.
Reversible: no
Disclaimer
Toxicity: Harmful (C)
General description
A cell-permeable marine toxin from the Red Sea sponge Latrunculia magnifica that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos.
Other Notes
Ayscough, K.R., et al. 1997. J. Cell Biol.137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Schatten, G., et al. 1986. Exp. Cell Res.166, 191.
Spector, I., et al. 1983. Science219, 493.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Schatten, G., et al. 1986. Exp. Cell Res.166, 191.
Spector, I., et al. 1983. Science219, 493.
Packaging
Packaged under inert gas
Physical form
A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428021 in DMSO.
Preparation Note
Following initial use, aliquot and freeze (-20°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F - (refers to pure substance)
flash_point_c
87 °C - (refers to pure substance)
法规信息
高风险级别生物产品--毒素类产品
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