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428026

Latrunculin A

Name: Latrunculin A
Brand: MM

from Latrunculia magnifica, ≥85% (HPLC), liquid, actin polymerization inhibitor, Calbiochem

别名:

InSolution Latrunculin A, Latrunculia magnifica

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关于此项目

经验公式（希尔记法）:

C₂₂H₃₁NO₅S

分子量:

421.55

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥85% (HPLC)

Form:

liquid

Quality level:

100

Storage condition:

OK to freeze, desiccated (hygroscopic), protect from light

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属性

产品名称

Latrunculin A, Latrunculia magnifica, InSolution, ≥85%, 1 mM in DMSO, marine toxin that disrupts microfilament organization in cultured cells

Quality Level

100

assay

≥85% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

shipped in

wet ice

storage temp.

−20°C

说明

General description

A cell-permeable marine toxin from the Red Sea sponge Latrunculia magnifica that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (K_d = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Inhibitor of microfilament-mediated processes in sperm, eggs, and embryos

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Physical form

A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428021 in DMSO.

Preparation Note

Following initial use, aliquot and freeze (-20°C).

Other Notes

Ayscough, K.R., et al. 1997. J. Cell Biol.137, 399.
Spector, I., et al. 1989. Cell Motil. Cytoskeleton13, 127.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Schatten, G., et al. 1986. Exp. Cell Res.166, 191.
Spector, I., et al. 1983. Science219, 493.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - (refers to pure substance)

flash_point_c

87 °C - (refers to pure substance)

法规信息

高风险级别生物产品--毒素类产品

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货号	GTIN
428026-50UG	04055977210514