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Merck
CN

434692

Sigma-Aldrich

Leukotriene C₄ - CAS 72025-60-6 - Calbiochem

别名:

Leukotriene C₄ - CAS 72025-60-6 - Calbiochem, LTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7- trans-9- trans-11- cis-14- cis-eicosatetraenoic Acid

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关于此项目

经验公式（希尔记法）:
C30H47N3O9S
化学文摘社编号:
72025-60-6
分子量:
625.77
MDL编号:
MFCD00151079
UNSPSC代码:
12352211

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方案

≥98% (HPLC)

质量水平

100

表单

liquid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

运输

wet ice

储存温度

−70°C

InChI

1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,12-11+,16-13+/t22-,23-,24-,25+/m0/s1

InChI key

GWNVDXQDILPJIG-NXOLIXFESA-N

一般描述

This product has been discontinued.



Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.

Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.

生化/生理作用

Cell permeable: no
Primary Target
Microsomal glutathione transferase-1
Product does not compete with ATP.
Reversible: no

外形

In MeOH:NH₄OAc buffer (65:35), pH 5.6.

制备说明

Following initial thaw, aliquor and freeze (-70°C).

其他说明

Bannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Flammable (J)

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

法规信息

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