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Merck
CN

445825

DL-2-Mercaptomethyl-3-guanidinoethylthiopropanoic Acid - Calbiochem

别名:

Plummer’s Inhibitor

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assay

≥95% (HPLC)

Quality Level

form

solid

color

off-white

solubility

degassed water: soluble

General description

Potent reversible inhibitor of human plasma carboxypeptidase N (Ki = 2 nM).
Potent reversible inhibitor of human plasma carboxypeptidase N (Ki = 2 nM). Inhibits hydrolysis of bradykinin.

Biochem/physiol Actions

Target IC50:2 nM against human plasma carboxypeptidase N

Preparation Note

Addition of a small amount of NaOH or NH₄OH may be necessary to achieve complete solubilization.
Unstable in solution; reconstitute just prior to use.


存储类别

10-13 - German Storage Class 10 to 13

法规信息

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A potent mercapto bi-product analogue inhibitor for human carboxypeptidase N.
T H Plummer et al.
Biochemical and biophysical research communications, 98(2), 448-454 (1981-01-30)