Monocyte Chemotactic Protein-1, Human, Recombinant, E. coli

Recombinant, human monocyte chemotactic protein-1 expressed in E. coli. A potent chemoattractant for human monocytes and mouse peritoneal macrophages. Its effects are proposed to be mediated by P₂-integrins.

ED₅₀ = 5-20 ng/ml as measured by its monocyte chemotactic activity

Lyophilized from sterile-filtered PBS, 50 µg BSA/µg MCP-1.

Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 1 year at -70°C.

Reconstitute to a concentration ≥10 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.

Hosang, K., et al. 1994. Biochem. Biophys. Res. Commun.199, 962.
Luini, W., et al. 1994. Cytokine 6, 28.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Toxicity: Standard Handling (A)