487955
NOC-12
A nitric oxide (NO) donor similar to NOC-5 and NOC-7 but with a much longer half-life of NO release.
别名:
NOC-12, N-Ethyl-2-(1-ethyl-2-hydroxy-2-nitrosohydrazino)ethanamine
质量水平
方案
≥90% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
颜色
white
溶解性
0.1 M NaOH: soluble
water: soluble
运输
ambient
储存温度
−20°C
InChI
1S/C6H16N4O2/c1-3-7-5-6-9(4-2)10(12)8-11/h7,11H,3-6H2,1-2H3/b10-8-
InChI key
DPKCLDSTXVCYSN-NTMALXAHSA-N
一般描述
A nitric oxide (NO) donor similar to NOC-5 (Cat. No. 487950) and NOC-7 (Cat. No. 487952) but with a much longer half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 327 minutes at 22°C. Inhibits the proliferation of arterial smooth muscle cells in a dose-dependent manner. Relatively stable in alkaline solution (pH ≥10.0).
生化/生理作用
Cell permeable: no
Product does not compete with ATP.
Reversible: no
其他说明
Ambalavanan, N., et al. 1999. Biol. Neonate76, 291.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Irritant (B)
警示用语：
Danger
危险声明
危险分类
Self-react. C
储存分类代码
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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