方案
≥97% (SDS-PAGE)
质量水平
表单
lyophilized
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
杂质
≤1.0 EU/μg protein Endotoxin
运输
ambient
储存温度
−20°C
一般描述
Recombinant, human neuregulin 1-β1/heregulin 1-β1 epidermal growth factor-like domain (NRG1-β1/HRG1-β1 EGF Domain), consisting of amino acids 176-246 and expressed in E. coli. All NRG1 isoforms contain an EGF-like domain that is required for binding directly to the ErbB3 or ErbB4 receptor tyrosine kinases.
生化/生理作用
ED₅₀ = 0.06-0.3 ng/ml as measured in a serum-free proliferation assay using MCF-7 human breast adenocarcinoma cells.
警告
Toxicity: Standard Handling (A)
外形
Lyophilized from 0.2 µm filtered acetonitrile, TFA, BSA.
重悬
Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Reconstitute to 100 µg/ml with sterile PBS containing ≥1% human or bovine serum albumin.
其他说明
Buonanno, A., and Fischbach, G.D. 2001. Curr. Opin. Neurobiol.11, 287.
Adlkofer, K. and Lai, C. 2000. Glia29, 104.
Garratt, A.N. et al. 2000. BioEssays22, 987.
Karey, K.P., et al. 1988. Cancer Res.48, 4083.
Adlkofer, K. and Lai, C. 2000. Glia29, 104.
Garratt, A.N. et al. 2000. BioEssays22, 987.
Karey, K.P., et al. 1988. Cancer Res.48, 4083.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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