5.04274
CB2 agonist, JWH 015 - CAS 155471-08-2 - Calbiochem
别名:
CB2 agonist, JWH 015 - CAS 155471-08-2 - Calbiochem, (2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone, JWH-015, JWH 015
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关于此项目
assay
≥95% (HPLC)
form
solid
potency
13.8 nM Ki
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 10 mg/mL
storage temp.
−20°C
General description
A potent and highly selective agonist for cannabinoid subtye 2 (CB2) receptor. Affinity for CB2 (Ki = 13.8 nM) is more than 28-fold higher than that for CB1 (Ki = 383 nM) receptors.
Biochem/physiol Actions
Primary Target
CB2 receptor
CB2 receptor
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Aung, M., et al. 2000. Drug Alcohol Depend.60, 133.
Murataeva, N., et al. 2012. Pharmacol. Res.66, 437.
Marriott, K., et al. 2008. Curr Top Med Chem.8, 187.
Ghosh, S., et al. 2006. Mol Immunol.43, 2169.
Murataeva, N., et al. 2012. Pharmacol. Res.66, 437.
Marriott, K., et al. 2008. Curr Top Med Chem.8, 187.
Ghosh, S., et al. 2006. Mol Immunol.43, 2169.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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