5.04777
Yohimbine Hydrochloride
别名:
Yohimbine Hydrochloride, 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride, α₂-Adrenoceptor Antagonist, Yohimbine Hydrochloride
方案
≥98% (HPLC)
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
pale yellow
溶解性
DMSO: 25 mM
储存温度
−20°C
InChI
1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24;/h2-5,12,15,17-19,22,24H,6-11H2,1H3;1H/t12-,15-,17-,18-,19+;/m0./s1
InChI key
PIPZGJSEDRMUAW-VJDCAHTMSA-N
一般描述
A potent antagonist for α2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human α2a, α2B and α2C receptors respectively). Often used as pharmacological stressor in animal studies.
Yohimbine Hydrochloride is a potent antagonist for α₂-adrenoceptors, α2B and α2C receptors respectively).
生化/生理作用
Primary Target
→₂-adrenoceptor
→₂-adrenoceptor
制备说明
Following reconstitution, aliquot and freeze (-20°c). Stock solutions are stable for up to 3 months at -20°C.
Slight warming is required for complete solubilization.
其他说明
Calu, D., et al. 2013. J. Neurosci.33, 214.
Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol.325, 136.
Goldberg, K., et al. 1987. Pharmacol. Rev.35, 143.
Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther.303, 979.
Doxey, L., et al. 1984. Naunyn Schmiedebergs Arch. Pharmacol.325, 136.
Goldberg, K., et al. 1987. Pharmacol. Rev.35, 143.
Lalchandani, et al. 2002. J. Pharmacol. Exp. Ther.303, 979.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Toxic (F)
警示用语：
Danger
危险声明
危险分类
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
储存分类代码
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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