方案
≥98% (NMR)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
off-white
溶解性
water: 100 mM
储存温度
2-8°C
一般描述
A highly potent antagonist slightly selective for NR2A over other subtype NMDA receptors (Ki = 0.041, 0.27, 0.63 and 1.99 µM for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively). Commonly used for various research in brain functions and disorders that neurotransmissions via NMDA receptors are involved.
生化/生理作用
Primary Target
NMDA receptors
NMDA receptors
Target Ki: 0.041, 0.27, 0.63 and 1.99 →M for NMDA subtypes NR2A, NR2B, NR2C, and NR2D, respectively.
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Murphy, R., et al. 2012. Psychopharmacol.219, 401.
Paoletti, P., et al. 2007. Curr. Opin. Pharmacol.7, 47.
Feng, B., et al. 2004. Br. J. Pharmacol.141, 508.
Lowe, A., et al. 1990. Neurosci. Lett.113, 315.
Paoletti, P., et al. 2007. Curr. Opin. Pharmacol.7, 47.
Feng, B., et al. 2004. Br. J. Pharmacol.141, 508.
Lowe, A., et al. 1990. Neurosci. Lett.113, 315.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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