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5.04913

Aniracetam

Name: Aniracetam
Brand: MM

别名:

Aniracetam, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet, Memodrin, Referan, Memodrin, Referan, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet

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关于此项目

经验公式（希尔记法）:

C₁₂H₁₃NO₃

化学文摘社编号:

72432-10-1

分子量:

219.24

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00153767

Assay:

≥99% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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属性

assay

≥99% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 100 mM

storage temp.

2-8°C

SMILES string

N2(CCCC2=O)C(=O)c1ccc(cc1)OC

InChI

1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3

InChI key

ZXNRTKGTQJPIJK-UHFFFAOYSA-N

说明

General description

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/physiol Actions

Primary Target
AMPA receptors

Other Notes

Koliaki, C., et al. 2012. CNS Neuroscience & Therapeutics.18, 302.
Lynch, G., et al. 2011. Pharmacol. Biochem. Behav.99, 116.
Nakamura, K., et al. 2001. Eur. J. Pharmacol.420, 33.
Ito, I. et al., 1990. J. Physiol.424, 553.
Isaacson et al., 1991. PNAS.88, 1093.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c