跳转至内容
Merck
CN

5.05208

Methyllycaconitine Citrate - CAS 21019-30-7 - Calbiochem

别名:

Methyllycaconitine Citrate - CAS 21019-30-7 - Calbiochem, AChR Receptor Antagonist, Methyllycaconitine Citrate, alpha7beta2 recptor Antagonist, Methyllycaconitine Citrate, Methyllycaconitine; α7-Nicotinic Receptor Antagonist, Methyllycaconitine Citrate, Neuronal Nicotinic Receptor Antagonist, Methyllycacon, AChR Receptor Antagonist, Methyllycaconitine Citrate, alpha7beta2 recptor Antagonist, Methyllycaconitine Citrate, Methyllycaconitine; α7-Nicotinic Receptor Antagonist, Methyllycaconitine Citrate, Neuronal Nicotinic Receptor Antagonist, Methyllycaconi

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C37H50N2O10 · xC6H8O7
化学文摘社编号:
21019-30-7
分子量:
682.80 (salt-free basis)
UNSPSC Code:
12352200

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

InChI key

XLTANAWLDBYGFU-ACDIZPBGSA-N

InChI

1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19?,21-,22-,24+,25+,27-,28+,29-,30+,33?,34+,35-,36+,37-/m1/s1

assay

≥97% (HPLC)

form

solid

potency

1.4 nM Ki

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

water: 100 mM

storage temp.

−20°C

General description

A potent antagonist highly selective for AChRs with α7 subunit (Ki = 1.4 nM for α7 subunit and >40 nM for α4β2 and α6β2 receptors). Frequently used in assessing the functional roles of AChRs with α7 subunit in brain functions and disorders (i.e. inflammatory and chronic neuropathic pain and parkinsonian neurodegeneration).

Biochem/physiol Actions

Primary Target
a7 AchR

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Suzuki, S., et al. 2013. J. Neurosci. Res.91, 462.
Freitas, K., et al. 2013. Neuropharmacol.65, 156.
Sheeja, N., et al. 2012. Hippocampus.22, 335.
Xiong, Y., et al. 2010. Pharmacol. Biochem. & Beha.95, 192.

Whiteaker, P., et al. 1999. Eur. J. Neurosci.11, 96.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

法规信息

新产品
此项目有

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持