5.05773
Bethanechol Chloride
别名:
Carbamyl-β-methylcholine chloride, Carbamyl-β-methylcholine chloride, Muscarinic Acetylcholine Receptors (mAChR) Agonist, Bethanechol Chloride, Bethanechol chloride
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关于此项目
assay
≥98% (TLC)
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 100 mM
storage temp.
2-8°C
SMILES string
Cl.CC(C[N](C)(C)C)OC(N)=O
InChI
1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H
InChI key
AIRHOJQHGLTTTB-UHFFFAOYSA-N
General description
An agonist selective for Muscarinic Acetylcholine Receptors (mAChRs, EC50 = 7, 14.5, 35 and 32 µM for M4, M3, M1 and M5 respectively) with no effect on nicotinic receptors. It is not a substrate for acetylcholinesterase therefore has longer duration of action than acetylcholine. Clinically used to treat certain bladder related conditions.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Manchana T., et al., 2011. Int. J. Gynecol. Cancer.21, 730.
Liu, L., et al. 2003. Br. J. Pharmacol.138, 70.
Liu, L., et al. 2003. Br. J. Pharmacol.138, 70.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
