528120
PIPER - CAS 213416-70-7 - Calbiochem
A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA.
别名:
PIPER - CAS 213416-70-7 - Calbiochem, N,Nʹ- bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV, N,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV
方案
≥95% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
dark purple
溶解性
5% acetic acid: 50 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May also be useful as an antiproliferative agent.
A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May be useful as an antiproliferative agent.
生化/生理作用
Cell permeable: no
Primary Target
human telomerase
human telomerase
Product does not compete with ATP.
Reversible: no
包装
Packaged under inert gas
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
其他说明
Han, H., et al. 1999. Biochemistry38, 6981.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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