539183
Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem
别名:
Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem, β-Lactam 3
form
solid
assay
≥95% (NMR)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
color
off-white
solubility
DMSO: 10 mg/mL
shipped in
wet ice
storage temp.
−70°C
General description
This product has been discontinued.
A β-lactam analog of Proteasome Inhibitor VII, Antiprotealide (Cat. No. 539179) that acts as a selective and irreversible inhibitor of the 20S proteasome. While the rate of proteasome inhibition is slower than Omuralide (Cat. No. 426102), β-lactam 3 displays prolonged aqueous stability and therefore may be better suited for biological evaluation.
Biochem/physiol Actions
Cell permeable: no
Primary Target
20S proteasome
20S proteasome
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
Other Notes
Hogan, P.C. and Corey, E.J. 2005. J. Am. Chem. Soc.127, 15386.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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