539560
PKC Inhibitor Peptide 19-36
The PKC Inhibitor Peptide 19-36 controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
PKC Inhibitor Peptide 19-36, Protein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white to off-white
solubility
water: 0.1%
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
Acts as pseudosubstrate by binding to the active sites of protein kinase C. A potent, reversible, and substrate competitive inhibitor of protein kinase C (Ki = 147 nM) but not of protein kinase A (IC50 = 423 µM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
PKC
PKC
Product does not compete with ATP.
Reversible: yes
Target Ki: 147 nM against protein kinase C
Packaging
Yes
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.
Other Notes
H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH
Makowske, M. and Rosen, O.M. 1989. J. Biol. Chem.264, 16155.
House, C. and Kemp, B.E. 1987. Science238, 1726.
House, C. and Kemp, B.E. 1987. Science238, 1726.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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