539560
PKC Inhibitor Peptide 19-36
The PKC Inhibitor Peptide 19-36 controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
PKC Inhibitor Peptide 19-36, Protein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN
质量水平
方案
≥95% (HPLC)
表单
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white to off-white
溶解性
water: 0.1%
运输
ambient
储存温度
−20°C
一般描述
Acts as pseudosubstrate by binding to the active sites of protein kinase C. A potent, reversible, and substrate competitive inhibitor of protein kinase C (Ki = 147 nM) but not of protein kinase A (IC50 = 423 µM).
生化/生理作用
Cell permeable: no
Primary Target
PKC
PKC
Product does not compete with ATP.
Reversible: yes
Target Ki: 147 nM against protein kinase C
包装
Yes
外形
Supplied as a trifluoroacetate salt.
制备说明
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.
其他说明
H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH
Makowske, M. and Rosen, O.M. 1989. J. Biol. Chem.264, 16155.
House, C. and Kemp, B.E. 1987. Science238, 1726.
House, C. and Kemp, B.E. 1987. Science238, 1726.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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