540200
PTP Inhibitor I - CAS 2491-38-5 - Calbiochem
别名:
PTP Inhibitor I - CAS 2491-38-5 - Calbiochem, Protein Tyrosine Phosphatase Inhibitor I, α-Bromo-4-hydroxyacetophenone, 4-Hydroxyphenacyl Br, SHP1 Inhibitor II
InChI
1S/C8H7BrO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,10H,5H2
InChI key
LJYOFQHKEWTQRH-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
powder
potency
43 μM IC50
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 200 mg/mL
shipped in
wet ice
storage temp.
−70°C
Quality Level
General description
This product has been discontinued.
A potent, cell-permeable, and covalent protein tyrosine phosphatase (PTP) inhibitor. Inhibits SHP-1 (ΔSH2), the catalytic domain of the SH2 domain-containing phosphatase SHP-1 (Ki = 43 µM), and PTPIB (Ki = 42 µM). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm.
Biochem/physiol Actions
SHP-1
Packaging
Preparation Note
Other Notes
Legal Information
Disclaimer
存储类别
8A - Combustible corrosive hazardous materials
法规信息
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