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Merck
CN

559307

Sigma-Aldrich

Sangivamycin - CAS 18417-89-5 - Calbiochem

别名:

Sangivamycin - CAS 18417-89-5 - Calbiochem, 7-Deaza-7-carbamoyladenosine, NSC-65346

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关于此项目

经验公式（希尔记法）:
C12H15N5O5
化学文摘社编号:
18417-89-5
分子量:
309.28
MDL编号:
MFCD00214391
UNSPSC代码:
12352200

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方案

≥98% (HPLC)

质量水平

100

表单

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white

溶解性

0.1 M KOH: 5 mg/mL

运输

ambient

储存温度

2-8°C

InChI

1S/C12H15N5O5/c13-9-6-4(10(14)21)1-17(11(6)16-3-15-9)12-8(20)7(19)5(2-18)22-12/h1,3,5,7-8,12,18-20H,2H2,(H2,14,21)(H2,13,15,16)

InChI key

OBZJZDHRXBKKTJ-UHFFFAOYSA-N

一般描述

This product has been discontinued.



A cytotoxic purine nucleoside active against human cytomegalovirus (HCMV). A cell-permeable, reversible, selective, and potent protein kinase C (PKC) inhibitor (IC50 = 10 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to histone and lipid cofactors.

A cytotoxic purine nucleoside active against human cytomegalovirus (HCMV). A cell-permeable, reversible, selective, and potent protein kinase C (PKC) inhibitor (IC50 = 10 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to histone and lipid cofactors.

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Target IC50: 10 µM against PKC

其他说明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Greene, N.M., et al. 1995. J. Biol. Chem. 270, 6710.
Osada, H., et al. 1989. J. Antibiot. 42, 402.
Loomis, C.R. and Bell, R.M. 1988. J. Biol. Chem. 263, 1682.
Turk, S.R., et al. 1987. Antimicrob. Agents Chemother. 31, 544.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Highly Toxic (H)

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

法规信息

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