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Merck
CN

559324

Sigma-Aldrich

p38α, His•Tag®, Human, Recombinant, E. coli

别名:

CSBP, Mxi2, p38, RK, SAPK2α, p38α

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UNSPSC代码:
12352202
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方案

≥95% (SDS-PAGE)

质量水平

表单

liquid

比活

≥12,000 units/mg protein

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
avoid repeated freeze/thaw cycles

异质活性

Proteases, none detected

运输

wet ice

储存温度

−70°C

一般描述

This product has been discontinued.



Recombinant, human p38α/SAPK2 fused to a His•Tag sequence and expressed in E. coli. Highly active form produced by phosphorylation of the purified SAP Kinase in vitro with MKK6. Suitable for labeling SAP Kinase substrates.

Recombinant, human p38α/SAPK2 fused to a His•Tag sequence and expressed in E. coli. Highly active form produced by phosphorylation of purified SAPK2α in vitro with MKK6. Suitable for labeling SAPK2α substrates.

包装

Please refer to vial label for lot-specific concentration.

外形

In 150 mM NaCl, 25 mM Tris-HCl, 1 mM DTT, 50% glycerol, pH 8.5.

制备说明

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Guo, X., et al. 2003. J. Biol. Chem.278, 22237.
Sanz-Moreno V., et al. 2003. Mol. Cell Biol.23, 3079.
One unit is defined as the amount of enzyme that will catalyze the transfer of 1 pmol of phosphate to myelin basic protein (MBP) per min at 30°C.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Standard Handling (A)

法规信息

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Brian L Olson et al.
Genes & development, 22(2), 252-264 (2008-01-17)
Peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator-1alpha (PGC-1alpha) is a highly regulated transcriptional coactivator that coordinates energy metabolism in mammals. Misregulation of PGC-1alpha has been implicated in the pathogenesis of several human diseases, including diabetes, obesity, and neurological disorders. We identified

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