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经验公式(希尔记法):
C6H10N4O2 · xHCl
化学文摘社编号:
分子量:
170.17 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
产品名称
SIN-1,盐酸盐, Nitric oxide (NO) donor.
SMILES string
[Cl-].[n]2(n[o+]c(c2)N)N1CCOCC1
InChI
1S/C6H11N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5H,1-4,7H2;1H/q+1;/p-1
InChI key
ZRFWHHCXSSACAW-UHFFFAOYSA-M
description
RTECS - WU7687800
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 10 mg/mL, ethanol: 10 mg/mL, water: 25 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
相关类别
General description
一氧化氮(NO)供体。自发分解产生NO和超氧阴离子自由基。还可抑制受刺激血小板释放纤溶酶原激活物抑制剂(PAI)。在水溶液中不稳定。
Biochem/physiol Actions
主要靶标
一氧化氮(NO)供体
一氧化氮(NO)供体
产物不与ATP竞争。
可逆:否
细胞可渗透性:否
Preparation Note
在水溶液中不稳定;仅在使用前进行复溶。复溶后,等分并冷冻保存(-20°C)。
来自目录:
描述字段-添加“在水溶液中不稳定”
来自目录:
描述字段-添加“在水溶液中不稳定”
Other Notes
Gow, A.J., et al. 2000.Am. J. Physiol. 278, C1099.
Gergel, D., et al. 1995.J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993.FEBS Lett.315, 139.
Lipton, S.A., et al. 1993.Nature364, 626.
Drummer, C., et al. 1991.Thromb.Res.63, 553.
Omar, B.A., et al. 1990.Free Radical Biol. Med.9, 465
Gergel, D., et al. 1995.J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993.FEBS Lett.315, 139.
Lipton, S.A., et al. 1993.Nature364, 626.
Drummer, C., et al. 1991.Thromb.Res.63, 553.
Omar, B.A., et al. 1990.Free Radical Biol. Med.9, 465
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性:有害(C)
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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