567703
Spermine NONOate
Complex of nitric oxide (NO) with spermine.
别名:
Spermine NONOate, N-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22
产品名称
Spermine NONOate, Complex of nitric oxide (NO) with spermine.
InChI
1S/C10H26N6O2/c11-5-3-8-13-7-1-2-9-15(10-4-6-12)16(18)14-17/h13,18H,1-12H2/p+3
InChI key
QPIOUFBAROSIAN-UHFFFAOYSA-Q
assay
≥98% (UV)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
0.1 M NaOH: soluble
water: soluble
shipped in
ambient
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Cell permeable: no
Primary Target
Convenient reagent for preparing aqueous solutions of NO
Convenient reagent for preparing aqueous solutions of NO
Product does not compete with ATP.
Reversible: no
Disclaimer
Toxicity: Standard Handling (A)
General description
Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½)in PBS, pH 7.4 is 230 minutes at 22°C. Relatively stable in alkaline solution (≥pH 10.0).
Other Notes
Ramamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.
Hrabie, J.A., et al. 1993. J. Org. Chem.58, 1472.
Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA90, 9813.
Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.
Packaging
Packaged under inert gas
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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