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573096

STAT3 Inhibitor Peptide, Cell-Permeable

≥95% (HPLC), lyophilized solid, STAT3 inhibitor, Calbiochem®

别名:

STAT3 Inhibitor Peptide, Cell-Permeable, PpYLKTK-mts, STAT3 Inhibitor IV

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关于此项目

经验公式（希尔记法）:
C92H157N20O24P
分子量:
1958.32
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
100
Storage condition:
OK to freeze, desiccated (hygroscopic)
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产品名称

STAT3 Inhibitor Peptide, Cell-Permeable, The STAT3 Inhibitor Peptide, Cell-Permeable controls the biological activity of STAT3.

Quality Level

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

Supplied as a trifluoroacetate salt.
A cell-permeable analog of the Stat3-SH2 domain-binding phosphopeptide (Cat. No. 573095) that contains a C-terminal mts (membrane translocating sequence) and acts as a highly selective, potent blocker of Stat3 activation. Also suppresses constitutive Stat-3 dependent Src transformation with no effect on Stat-3 independent Ras transformation. The unphosphorylated inactive control peptide is also available under Cat. No. 573105.

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Blocker of Stat3 activation
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Other Notes

H-Pro-Tyr-(PO₃H₂)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH
Turkson, J., et al. 2001. J. Biol. Chem.276, 45443.
Rojas, M., et al. 1998. Nat. Biotechnol.16, 370.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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全球贸易项目编号

货号GTIN
573096-1MG07790788051730
573096-5MG07790788051747