A heterobifunctional cross-linker. Reagent similar to SATA, useful for introducing protected thiol groups into a variety of proteins. Treatment with DTT releases the chromophore 2-pyridylthione and a mercaptopropionyl-modified amine. This thiolated biomolecule can then be coupled to a second biomolecule through an iodoacetamide or maleimide group. In addition, the thiolated biomolecule can be reacted with a second pyridyldisulfide-containing biomolecule.

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.