Quality Level
suitability
suitable for chromatography
SMILES string
OC(=O)C(F)(F)F
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
General description
Trifluoroaceticacid (TFA) is used as an additive in HPLC and LC-MS analyses to improve theseparation of basic compounds.
Application
Trifluoroacetic acid can be used as:
- Ion-pairing reagent in reversed-phase liquid chromatography (RPLC) for peptide separation.
- An acidic additive in the mobile phase for chiral supercritical fluid chromatography.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 2
法规信息
新产品
此项目有
Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography
De Klerck K, et al.
Journal of Chromatography A, 1234, 72-79 (2012)
Utility of retention prediction model for investigation of peptide separation selectivity in reversed-phase liquid chromatography: impact of concentration of trifluoroacetic acid, column temperature, gradient slope and type of stationary phase
Analytical Chemistry, 82(1), 265-275 (2010)