assay
≥98% (TLC)
Quality Segment
form
solid
color
yellow
solubility
ethanol: 10 mg/mL, DMSO: soluble, acetic acid: soluble
General description
An inactive compound that can be used as a negative control for inhibition of EGFR (IC50 >1250 μM for EGFR kinase). Has been shown to inhibit IL-2 stimulated Tyk-2 phosphorylation in ConA-activated T cells.
Biochem/physiol Actions
negative control for inhibition of EGFR
Target IC<SUB>50</SUB>:>1250 μM for EGFR kinase
Target IC<SUB>50</SUB>:>1250 μM for EGFR kinase
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
存储类别
10-13 - German Storage Class 10 to 13