688100
YC-1
A nitric oxide-independent, superoxide-sensitive activator of soluble guanylyl cyclase.
别名:
YC-1, 3-(5ʹ-Hydroxymethyl-2ʹ-furyl)-1-benzylindazole
质量水平
方案
≥98% (HPLC)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated
protect from light
颜色
off-white to pale yellow
溶解性
DMSO: 10 mg/mL
methanol: 5 mg/mL
运输
ambient
储存温度
−20°C
InChI
1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
InChI key
OQQVFCKUDYMWGV-UHFFFAOYSA-N
一般描述
A nitric oxide-independent, superoxide-sensitive activator of soluble guanylyl cyclase. Inhibits platelet adhesion to collagen and acts as an antithrombotic agent. Reported to reduce HIF-1α levels and xenograft growth.
生化/生理作用
Cell permeable: no
Primary Target
Activator of soluble guanylyl cyclase
Activator of soluble guanylyl cyclase
Product does not compete with ATP.
Reversible: no
制备说明
Following reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 3 months at -20°C.
其他说明
Yeo, E.J., et al. 2003. J. Natl Cancer Inst.95, 516.
Mulsch, A., et al. 1997. Br. J. Pharmacol. 120, 681.
Teng, C.M., et al. 1997. Eur. J. Pharmacol. 320, 161.
Wu, C.C., et al. 1997. Biochem. Biophys. Res. Commun. 231, 412.
Wu, C.C., et al. 1995. Br. J. Pharmacol. 116, 1973.
Mulsch, A., et al. 1997. Br. J. Pharmacol. 120, 681.
Teng, C.M., et al. 1997. Eur. J. Pharmacol. 320, 161.
Wu, C.C., et al. 1997. Biochem. Biophys. Res. Commun. 231, 412.
Wu, C.C., et al. 1995. Br. J. Pharmacol. 116, 1973.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Toxicity: Standard Handling (A)
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持